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Activation of the Nrf2/ARE pathway can mitigate these effects by enhancing the bodys antioxidant capacity and reducing inflammation

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Observed effects are documented as changes in metabolic markers , insulin-related activity , or other measurable biological responses specific to the research system used

The antidepressant-like, pro-neurogenic and neuroprotective effects of exercise were associated with the FNDC5/Irisin pathway (Gruhn et al., 2021)