As a JAMA Dermatology editorial board member, I'm proud the journal is investing in this evidence base
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It's estimated that almost 40% of the US population is B12 deficient, ranging from mild deficiencies that can cause weakness, tiredness, mood changes and neurological problems, to significant deficiencies that are associated with anemia, easy bruising, numbness in the fingers and toes, difficult walking, depression, memory loss and dementia
Possible mild effects may include: Temporary redness
Notably, patients with metabolic syndrome or T2DM exhibit abnormal enlargement and biotransformation of EAT and experience higher relative event rates compared to obese individuals with lower EAT volume (109)