Spermatidic giant cells were observed in monkeys after 6-month treatment at 30 mg/kg/day in addition to vacuolation of seminiferous tubular epithelium

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Epithalon, upon delivery, appeared to inhibit the process of metastasis in the mice, preventing tumor cell cycle and growth
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Similarly, mice with LAMP-2 knocked out show impaired autophagy and autophagosomes aggregation in cardiomyocytes, resulting in cardiac defects 148