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As active ingredients of distinct chemical structure exert pharmacological actions through differing signaling pathways, the effects of Chinese Yang/Qi-invigorating tonic botanical drugs/herbal formulations on CKD may result from synergistic interactions of multiple herbal components

It has been extensively studied for its role in gut healing, musculoskeletal recovery, tendon repair, and reducing inflammation

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Supplementary Table 1)

-Glutamyl cysteine and -glutamyl valine inhibit TNF- signaling in intestinal epithelial cells and reduce inflammation in a mouse model of colitis via allosteric activation of the calcium-sensing receptor