However, important safety considerations include: Risk of hypoglycaemia when used with insulin or sulfonylureas (dose reduction of these medications may be needed) Not recommended in severe gastrointestinal disease, including severe gastroparesis Risk of diabetic retinopathy complications, particularly in patients with pre-existing retinopathy Pancreatitis risk requiring immediate discontinuation if suspected Not recommended during pregnancy or breastfeeding Not sure where to start
Endothelial cell cystathionine lyase expression level modulates exercise capacity, vascular function, and myocardial ischemia reperfusion injury
Kanazawa I, Notsu M, Miyake H, Tanaka K, Sugimoto T
Weight loss may occur, though this can be difficult to interpret in patients using GLP-1 agents for weight management
How Klinic's Metabolic Health Program Works When you choose Klinic, the process to get started with tirzepatide treatment is simple and efficient