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It functions as a dual GIP/GLP-1 receptor agonist, meaning one peptide chain binds to and activates both the glucose-dependent insulinotropic polypeptide receptor and the GLP-1 receptor

This pathway mitigates GPX4 ubiquitination and subsequent degradation in non-small cell lung cancer (NSCLC) cells (99)

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In the present study, we examined the responses of these two small molecules to incretins and assessed the actions of metformin against incretin signaling