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Lysosomes undergo tubulation and swelling in the course of their normal function and under stress 32,33 , which raises the possibility that membrane shape changes could influence mTORC1 activation

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3.3 Antioxidant interventions for the preservation of ovarian tissue and oocyte in the context of in vitro fertilization Oxidative stress triggers apoptosis in granulosa cells, leading to the upregulation of pro-apoptotic factors and the downregulation of anti-apoptotic proteins, ultimately causing ovarian tissue damage and follicular depletion ( Table 1 (82, 83)