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They help: Stimulate insulin production after meals (lowering blood sugar) Slow gastric emptying (so patients feel full longer) Reduce appetite through direct effects on the brain While originally approved for type 2 diabetes, some GLP1s, such as Saxenda, Wegovy and Zepbound, carry FDA approval for weight loss in adults with a BMI of 30 or more, or 27 with other health issues like high blood pressure or cholesterol

Clinical and molecular genetics of Stickler syndrome

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ANGPTL3, angiopoietin-like protein 3

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