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[2 3] For Vascular Surgery, the reported design effect is 1.82, meaning that the 20 observations correspond to an effective sample size of only 11 (calculated as 11.0=20/1.82)

The abdomen provides consistent absorption, easy access for self-administration, and adequate fatty tissue in most individuals

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You may also be more likely to develop vitamin B-12 deficiency if you have: Atrophic gastritis, in which your stomach lining has thinned Pernicious anaemia, which makes it hard for your body to absorb vitamin B12 Conditions that affect your small intestine, such as Crohns disease, celiac disease, bacterial growth, or a parasite Immune system disorders, such as Graves disease or lupus Been taking certain medications that interfere with the absorption of B12