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Denominator (Type 2 Diabetes) The number of adult patients who have a type 2 diabetes diagnosis by the end of the quarter and a prescription or patient reported medication in the quarter Denominator (Overweight or Obese BMI) The number of adult patients who have a recorded body mass index (BMI) over 25 in the quarter, excluding encounters where the patient was pregnant

Preliminary data from the phase I trial demonstrated clinical responses with an acceptable tolerability profile in head and neck squamous cell carcinoma (HNSCC), ovarian cancer, NSCLC, HR + /HER2- breast cancer, triple negative breast cancer, and sarcoma, and PYX-201 monotherapy was granted FDA fast-track designation for patients with metastatic or recurrent HNSCC 243,244

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Searle T, Ali FR, Carolides S, Al-Niaimi F

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