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Human plasma samples were analyzed using both NMR spectroscopy and LCMS/MS for -HB and AcAc quantification, while acetone was measured by GCMS

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450 nm absorbance, OD450, measured by the microplate reader reflects the number of viable cells

Lactic Acid Content was evaluated using the Lactic Acid (LA) HPLC Assay Kit from Solaibao, China, according to the provided instructions