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Creatine monohydrate supplementation did not have a significant effect on endurance performance

Epigastric pain, early satiety, and gastroesophageal reflux are common initial symptoms of TD and gastrointestinal beriberi (19, 70)

157,158 Lactobacillus , a group of beneficial gram-positive lactic acid bacteria, is abundant in the intestine and contributes to improving the intestinal inflammatory response

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These combined actions have led to interest in its relevance for research models involving cardiovascular stress and impaired circulation.(23) Further animal-based investigations have reported protective effects in models of cardiac injury