In mouse models of type 2 diabetes induced by a highfat diet and streptozotocin, 4 weeks of 5amino1mq injection reduced fasting blood glucose by 25%30%, increased insulin secretion by over 20%, and significantly decreased cell apoptosis
These interconnected conditions arise from systemic metabolic dysfunction, characterized by insulin resistance, dyslipidemia, chronic low-grade inflammation, and ectopic fat deposition
Subsequent studies have expanded its research applications to include investigations into its anti-inflammatory, antioxidant, and gene-modulatory effects
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Benefits in High-Risk Patient Groups GLP-1 receptor agonists also show heart-protective effects in other vulnerable groups