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JAMA (2018) 319:24154

albumin, 4.2% vs 6.6%

However, these benefits were sensitive to preference weights, suggesting that even a 5% weight loss could be net beneficial for individuals with less concern about harm outcomes

The slight acidity of the solution (pH approximately 3.04.0 at 0.1% concentration) protonates basic amino acid residues on poorly water-soluble peptides, increasing their net positive charge and improving electrostatic interaction with the surrounding aqueous solvent a mechanism that dramatically increases the solubility of many lyophilised peptide preparations that resist dissolution in neutral or alkaline aqueous conditions

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