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In some cases, individuals may require alternative dosing strategies, customized formulations, or delivery options that are not commercially available

A long-standing hypothesis for why GLP-1 (and other gut peptides for that matter) are increased after RYGB is that the shorter length of small bowel leads to more rapid nutrient delivery further down into the GI tract where the majority of L-cells are located (62)

monitor renal function if volume depletion suspected

Lucke-Wold B, Seidel K, Udo R, Omalu B, Ornstein M, Nolan R et al (2017) Role of tau acetylation in Alzheimers disease and chronic traumatic encephalopathy: the way forward for successful treatment

Because on GLP-1 therapy, the barrier to eating is already high