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(PubMed) Harding AH, Wareham NJ, Bingham SA, et al

Abstract Importance Semaglutide and tirzepatide, the new generation of glucagon-like peptide-1 receptor agonist used to treat type 2 diabetes and obesity, were recently reported to be associated with increased risk of nonarteritic anterior ischemic optic neuropathy (NAION)

Most patients report noticing appetite changes within 37 days of their first semaglutide injection, though the full effect develops over 412 weeks as your dose escalates