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Weight loss itself independently increases diversity, while mandatory dietary modifications accompanying therapy represent major determinants of microbial structure (137, 138)

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The results showed that maternal RPM supplementation in late gestation promoted more significant global DNA methylation in the offsprings liver, accompanied by a general alteration in the hepatic transcriptome, proteome, and metabolome, favoring the enrichment in glucose and lipid metabolism, glutathione, and immune system pathways (Palombo et al., 2021)

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