tirzepatide weight loss data leads to reduction in people with obesity due to MC4R deficiency I wouldn't call 23% a

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Additionally, in a post-hoc analysis of the SURPASS-4 trials, tirzepatide showed a slower rate of eGFR decline and lower urinary albumin creatinine values as compared to patients who were treated with glargine insulin [75, 76]

Higher doses produce more noticeable retention

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