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Clinical trials indicate bethanechol is no more effective than placebo, and its use is associated with significant dose-dependent unpleasant side effects including blurred vision, bradycardia, bronchospasm, and GI upset (Barrett 1981

In the other direction, the brain may exert an influence on the gut, either via the autonomic and enteric nervous systems (downwards black arrows in Figure 2 ), or via activation of the Hypothalamus-Pituitary-Adrenal (HPA) axis (downwards red arrows in Figure 2 ), which will be examined in detail later

The Search for New Prostate Cancer Biomarkers Continues

Emerging braf mutations in cancer progression and their possible effects on transcriptional networks