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He hypothesized that lactic acidosis, increased concentration of Krebs cycle metabolites in urine, reduced levels of carnitine in plasma, decreased utilization of glucose in the brain, and lowered ATP levels in these patients are associated with mitochondrial dysfunction [66]

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It is an issue that future research needs to address

Epigenetic Signatures In Adipose Tissue Adipose tissue is metabolically active, and its behaviour can be influenced by epigenetic modifications changes that switch genes on or off without altering the underlying sequence

It helps neutralize free radicals, supports the immune system, and contributes to healthy aging