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The role of tirzepatide, dual GIP and GLP-1 receptor agonist, in the management of type 2 diabetes: the SURPASS Clinical Trials

The remarkable weight loss and glucose-lowering results achieved by the dual peptides paved the way for triple GIP/GLP-1/glucagon receptor triagonists with the hope that the new combinatorial approaches provide further synergistic metabolic effects

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As there are conflicting opinions on cyclosporin A in the literature, further in vitro and in vivo studies comparing all biological mechanisms involving the peptide would be appropriate

Physical changes such as fat loss or muscle growth typically take longer to become noticeable