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151 In rat NP cells, 152 GDF5 overexpression inhibited the secretion of TNF, IL1, PGE2, and NO in culture medium induced by LPS, inhibited the decrease in matrix production, including collagen II and aggrecan, and prevented NFB activation induced by LPS

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An important feature of astrocytic interaction with the BBB are the perivascular end feet which closely interact with the vascular walls and almost completely cover the entire cerebral vasculature [48]

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