Post hoc comparisons were performed using Bonferonni corrections
In essence, GL acts as a prodrug that requires enzymatic conversion to its active metabolite, GA, which then undergoes extensive enterohepatic circulation
Altered expression of glutamate transporters, including the cystineglutamate transporter (xCT) system, increases concentrations of extracellular glutamate, which contribute to epileptic discharge, tumour proliferation and peripheral excitotoxicity
Novel genetically encoded sensors allowed for accurate measurements of the subcellular dynamics of numerous metabolites, metals ions including calcium, H 2 O 2 , and pH [58]
BPC-157 is a synthetic pentadecapeptide studied in preclinical research for tissue-repair signaling, inflammation-pathway modulation, and gastrointestinal cytoprotective mechanisms