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For instance, a multicenter, placebo-controlled RCT could enroll several hundred heart failure patients on optimal therapy, randomizing them to add-on therapy with a purified TCM metabolite (at a standardized dose) versus placebo for 1 year

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J Young Pharm 1(1):82

In addition, it is one of a few antihyperglycemic agents associated with improvements in cardiovascular morbidity and mortality, which is a major cause of death in patients with type 2 diabetes