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The combination of BPC-157 and GHK-Cu appears to have synergistic effects, leading to more efficient and effective tissue repair

Funding This research received no external funding

Upregulation of sense gene via NAT degradation While the previously mentioned mechanisms function to upregulate the sense gene by directly acting upon the sense gene mRNA transcript, one limitation lies in the fact that uORFs only exist in approximately 50% of mammalian mRNA and within this 50%, not all are inhibitory [106, 107]

A SubQ injection in the same region bypasses this risk entirely

Experimental design considerations include the importance of timing senolytic administration relative to senescence induction or disease progression, as the biological context affects both efficacy and interpretation of results