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Prednisone, like other corticosteroids should not be administered concomitantly with: - Barbiturates, carbamazepine, phenytoin, rifampin or ephedrine: these drugs enhance the metabolism of corticosteroids reducing their therapeutic action

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The orbit of HD 80606b is almost like that of a comet, the researchers say, swinging sizzlingly close to its star and then back out to much greater distances over and over again every 111 days