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Assessment of pancreas safety in the development program of once-weekly GLP-1 receptor agonist dulaglutide

The odds ratio (OR) for the atherosclerotic retinopathy, after adjustment for hypertension, diabetes and hypercholesterolemia but not for age, was 0.39 (95% CI 0.240.64)

The oxidative pathway of cocaine yields several metabolites that trigger a greater degree of lipid peroxidation than cocaine itself, with simultaneous redox cycling and production of SO and lipid peroxyl radicals [331]

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These analogs are beneficial to diabetes patients in numerous ways as they work by enhancing glucose-dependent insulin secretion, suppressing elevated glucagon secretion, slowing gastric emptying, and suppressing appetite