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The recognition that oncometabolites play a central role in reprogramming the cancer epigenome has spurred the concept of 'metabostemness'

Moreover, arhalofenate acid activates AMPK downstream targets to participate in the regulation of mitochondrial function and maintain the function of mitochondrial crest (McWherter et al., 2018)

Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

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