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76 Van PuijenbroekE

Glucocorticoids: The Most Clinically Significant Interaction Glucocorticoids (prednisone, dexamethasone, hydrocortisone, budesonide) blunt the GH response to GHRH stimulation through at least three mechanisms: they increase hypothalamic somatostatin tone, they directly reduce somatotroph sensitivity to GHRH, and they suppress hepatic IGF-1 production independent of GH

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Activation of NQO1 in NQO1*2 polymorphic human leukemic HL-60 cells by diet-derived sulforaphane

Thus, the wildtype strain for NNT, the 6N substrain, generates more oxidant stress during APAP hepatotoxicity and suffers more severe liver injury compared to the NNT-deficient 6J substrain [132]