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Contraindications and precautions Consider avoiding DSIP or consulting a physician if: Pregnant or breastfeeding (insufficient safety data) Taking naloxone or other opioid antagonists (may block effects) Using medications metabolized by peptidases (potential interactions) History of immune disorders (theoretical immunogenicity concern) Already using multiple sleep medications Drug interactions Because DSIP degrades via amino-peptidases in blood, medications affecting these enzymes (like the ACE inhibitor captopril) could theoretically alter DSIP metabolism

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Therefore, if you are at high risk of a B12 deficiency, consult with your healthcare provider, who can run a blood test to check your B12 levels

Attend All Follow-Up Appointments: Regular check-ins and lab tests are necessary to monitor hormone levels and overall health

However, if you have Hashimotos disease or other types of autoimmune thyroid disorders, you may be sensitive to iodines harmful side effects