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In contrast, inhibiting astrocytic MAOB in the PL cortex did not affect the fear extinction retrieval (Supplementary Fig

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Age-related reduction of mitochondrial function is accompanied by a decline in the mitochondrial capacity for ATP production by oxidative phosphorylation [62], a reduction in the NAD + pool [63] by consuming processes (PARP, CD38, and SIRT1) [64], and further an increase in ROS generation by an inefficient electron transport chain (ETC) [26]

Cost efficiency at scale The most obvious advantage is price