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Clinical studies show that patients who use Ozempic experience significant weight loss compared to those using a placebo

[DOI] [PMC free article] [PubMed] [Google Scholar] 260.Sousa JR, Afreixo V, Carvalho J, Silva P

In the open-label SURMOUNT-5 trial (751 participants without diabetes), it was compared head-to-head with semaglutide

Berberine may help reduce body weight modestly (about two to four pounds over several weeks) and lower HbA1c levels, but it lacks the robust, consistent results seen with GLP-1 medications like Ozempic, which can produce 15 to 20 percent body weight reductions in clinical trials. Can GLP-1 Supplements Help With Weight Loss

Why A True GLP-1 Patch Is Unlikely To Work Right Now The primary limitation facing GLP-1 patches is biological rather than a lack of innovation