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This work was partially supported by National Natural Science Foundation of China 81872915 (M.-W.W.), 82073904 (M.-W.W.), 32071203 (L.H.Z), 81922071 (Y.Z.), 81773792 (D.Y.), 81973373 (D.Y.) and 21704064 (Q.T.Z.)

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When used appropriately and under medical supervision, they can support sustainable weight management as part of a broader health plan

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