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Semaglutide GLP-1 operates by reducing appetite through its action on receptors in the brain that mimic the effects of the GLP-1 hormone

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[1] [3] Importantly, patients should seek urgent medical attention if they experience severe or persistent abdominal pain (especially if radiating to the back), repeated vomiting, inability to keep fluids down, signs of dehydration, or jaundice, as these may indicate serious conditions such as pancreatitis or gallbladder disease

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These drugs are administered via subcutaneous injection or, in some cases, orally