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Weight loss itself often improves asthma symptoms because excess body weight increases pressure on the diaphragm and airways
These interactions highlight the ability of polyphenols to simultaneously address multiple pathological mechanisms in AD, including oxidative stress, neuroinflammation, and neurodegeneration, underscoring their potential as multitarget therapeutic agents for AD
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However, interpretation of reproductive outcomes is limited by residual confounding related to obesity severity, metabolic status, and prior treatment response [33, 34]
