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In this study, we revealed a significantly altered metabolic profile and immune responses in the peripheral system of Chinese patients with MS, in which metabolites of amino acids and sphingolipids might not only modulate peripheral proinflammatory responses but also drive the inflammatory process within the CNS

That conclusion must remain within the mouse experiment

Ramkhelawon B, Yang Y, van Gils JM, Hewing B, Rayner KJ, Parathath S, Guo L, Oldebeken S, Feig JL, Fisher EA, Moore KJ

doi: 10.1016/j.jpha.2023.12.005 83 MakishimaMLuTTXieWWhitfieldGKDomotoHEvansRMet al

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