We start with the patient: weight history, prior attempts, family history, blood pressure, glucose, cholesterol, liver markers, sleep, medications, mental health, alcohol use, menopause or PMOS context when relevant, and what the patient is actually trying to accomplish
There are now three GLP-1RA drugs approved in multiple countries [see Table 1] for chronic weight management, all of which are administered as injections: Wegovy (active substance semaglutide) and Saxenda (active substance liraglutide) from Novo Nordisk, and Mounjaro/Zepbound 1 (active substance tirzepatide) from Eli Lilly the latter being the first dual receptor agonist 2 drug approved
CMS was aiming for a critical mass of Part D sponsors to participate and established a threshold participation rate of 80% for 2027
10.1111/cas.14318 113 MekuriaA
Wegovy is metabolized and voided through the urine and bowel movements, Dr