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So, case closed, right

Typically, a B12 shot is administered in the upper buttocks, but some nurses will also use the shoulder

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Repeated, method-validated measurements (scintigraphy or C-breath testing) in the same participants at treatment start and after weeks of steady state, for cagrilintide monotherapy, to test the tachyphylaxis hypothesis directly

10.1016/S2213-2600(25)00019-0 Summary Keywords dipeptidyl peptidase 1 inhibitors, neutrophil serine proteases, non-cystic fibrosis bronchiectasis, chronic obstructive pulmonary disease, brensocatib, BI 1291583, HSK31858, clinical trials Citation Zhang D, Zhang W, Hu P and Zhang W (2025) Dipeptidyl peptidase 1 inhibitors for inflammatory respiratory diseases: mechanisms, clinical trials, and therapeutic prospects