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Goldstein, A.L., Hannappel, E

Elle peut se manifester notamment par des dmangeaisons, un eczma, une urticaire, des rougeurs sur la peau, voire une lsion localise de la peau pouvant voluer vers une destruction des cellules de la peau (ncrose), un dme pouvant tre svre (gonflement, dme de Quincke), ou un choc allergique (malaise intense gnralis)