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Dysregulation of GSH synthesis in aging and disease Although many conditions are known to be associated with low GSH levels (such as Parkinsons, HIV/AIDs, cystic fibrosis) (Townsend et al., 2003), not too many have been shown to be associated with a fall in GCL activity and/or GCL expression

However, if drug candidates that present serious health risks are investigated, such as certain antitumor drugs, patients who cannot readily benefit from the available therapies are assessed

Individual safety depends on metabolic health, baseline hormones, and drug interactions

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Annals of Agricultural and Environmental Medicine