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GLP-1 Medications Have Become a Line-Item Issue Over the past year or so, GLP-1 drugs have shifted from clinical innovation to a major budget concern

Insufficient duration and completeness of follow-up

A woody shrub from northeastern Asia with properties similar to those of ginseng, it has a long history of use to maximize athletic performance

MAY IMPROVE BODY COMPOSITION: Berberine may improve insulin sensitivity and reduce the body's fat storage

When to Call Your Doctor Severe abdominal pain Significant bloating or abdominal swelling Persistent nausea or vomiting Inability to pass gas, which can sometimes be a sign of a blockage in the colon Blood in the stool Black or tarry stools, which may indicate bleeding higher in the digestive tract Pencil-thin stools, which can be a sign of a narrowing or blockage Unexplained weight loss beyond what would be expected from the medication Fever A sudden change in bowel habits A lack of bowel movement for three to seven days, despite making lifestyle changes or taking over-the-counter medications New or worsening constipation after previously doing well on a GLP-1 medication Symptoms that persist for more than a few weeks despite treatment Resources We Trust Cleveland Clinic: Could You Be Pooping Better