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The GRADE trial suggested no difference in cognitive decline across insulin glargine, the DPP4 inhibitor sitagliptin, the sulfonylurea glimepiride, and the GLP1 receptor agonist liraglutide, but the mean age was 57.1 years, and SGLT2 inhibitors were not examined [54]

When observational studies report a small uptick in thyroid cancer overall, much of that signal involves papillary tumors, which complicates any simple story about C-cells and calcitonin

And, for the most part, I still believe that

For titration, it is advisable to increase 24U or 1020% to target glycemia