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2000, 21 (1): 67-86, viii

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Evidence of a role for one-carbon metabolism in blood pressure: can B vitamin intervention address the genetic risk of hypertension owing to a common folate polymorphism

Concurrent with this was an absence of proliferation of fibrous and reticular connective tissue or Kupffer cell activation

Citation255 Thus, a key focus for the clinical development of these therapies will be determining optimal dosing regimens and ensuring the safe use of these agents without disrupting vital physiological processes