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This selectivity is particularly important for individuals seeking pure fat reduction rather than body recomposition, those who do not want muscle hypertrophy for aesthetic or functional reasons, athletes in weight-class sports who need fat loss without muscle gain, individuals with contraindications to growth-promoting interventions, and those concerned about cell proliferation effects

However, their high costsoften exceeding $1,000 per month in the United States have remained a substantial barrier for many patients seeking long-term treatment

Certain bacteria species e.g

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Certain conditions are absolute contraindications for GLP-1 medications