doi: 10.3389/fmolb.2023.1210347 Received 22 April 2023 Accepted 06 September 2023 Published 15 September 2023 Volume 10 - 2023 Edited by Venkateswarlu Kanamarlapudi, Swansea University Medical School, United Kingdom Reviewed by Syed Muhammad Usama, University of Texas at San Antonio, United States Gregg Stanwood, Florida State University, United States Ming Yang, University of California, San Diego, United States Updates Copyright 2023 Xie, Wang, Pei and Chen
Oral supplementation of N acetylcysteine (NAC) and Se after TBI can alleviate oxidative stress by inhibiting ROS production and increasing the expression level of GPX, and at the same time downregulate the level of proinflammatory (IL1) cytokines and upregulate the level of antiinflammatory (IL4) cytokines to alleviate inflammatory stimulation, thereby showing a neuroprotective effect on TBI [184]
Inflammation is a pathological characteristic of aging
The growth typically presents as a swelling or mass that is sometimes rapidly enlarging and can be associated with pain or tenderness
Understanding these metabolic distinctions is crucial for comprehending why TAMs exert profound control over ferroptosis and how their reprogrammed immunometabolic states can influence tumor progression and therapeutic response, as shown in Figure 1
