One way to circumvent these challenges is exemplified by the therapeutic trajectory of glucagon-like peptide-1 (GLP-1) agonists
Convenient telehealth and messaging access: All medical visits take place online, and you can message your clinician anytime through the app for check-ins, updates, or guidance on your schedule
Tirzepatide targets two receptors
The efficacy and safety of tirzepatide, with a special focus on cardiovascular safety, were investigated in the 52-week SURPASS-4 trial testing tirzepatide versus insulin glargine in adults with T2D and a high cardiovascular risk under inadequate glycemic control at baseline on one to three oral glucose-lowering medications (metformin, sulfonylurea, SGLT-2 inhibitor) (54, 74)
In total, 36 studies were included in the qualitative analysis and 24 in the meta-analyses