Capillary electrophoresis-time of flight mass spectrometry (CE-TOFMS) was performed using an Agilent CE capillary electrophoresis system equipped with an Agilent 6210 time of flight mass spectrometer, Agilent 1100 isocratic high-performance liquid chromatography (HPLC) pump, Agilent G1603A CE-MS adapter kit, and Agilent G1607A CE-electrospray ionization (ESI)-MS sprayer kit (Agilent Technologies, Waldbronn, Germany)
A maximal single blood sample (~400 l) was obtained via a facial vein at 0, 2, 6, 10, 20, 30, 60 or 90 min after oral gavage ( n = 610 per time point per group), after which the animals were euthanised
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Glutathione levels in the left hippocampus were more sensitive
The scale is only one marker