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The MHRA advises stopping Wegovy at least two months before trying to conceive

In one study, called SUSTAIN-6, researchers found that people with type 2 diabetes who took Ozempic had a lower risk of major adverse cardiovascular events (MACE) such as heart attack, stroke, and cardiovascular death compared to those who took a placebo

Some practitioners implement cycling approaches (such as 12 weeks on, 4-8 weeks off), though no published research directly compares continuous versus cycled protocols

Dose adjustments cannot compensate for untreated hormonal instability or ongoing muscle loss

Psoas volume and fat content were assessed from liver MRIs and physical function was measured by chair-rise and gait speed tests at baseline and six months