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Support for this idea comes from the observation that tobacco overexpressing both -ECS and GSH-S had an ameliorated phenotype compared to tobacco expressing the first enzyme alone (Creissen et al., 1999)

depletion of LSD1 leads to increased LPAR6 expression, which promotes paxillin phosphorylation and enhances migration and invasion of androgen-independent PCa cells (67), indicating that both transcriptional and post-transcriptional epigenetic events contribute to LPA metabolic dysregulation

Oncogenesis 15 , 1 (2026)

Moreover, the activation of focal adhesion signaling through phosphorylation of FAK and paxillin is also posited to aid cell attachment and movement within the extracellular matrix, thus ultimately facilitating repair

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