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NNMT inhibition reduces consumption of nicotinamide (and of S-adenosylmethionine) by blocking the enzyme that would otherwise methylate them

Integr Comp Biol (2010) 50:86979.10.1093/icb/icq079 3 ChenCOuyangWYGriguraVZhouQCarnesKLimHet alERM is required for transcriptional control of the spermatogonial stem cell niche